Clinical Fellow: CAR T-Cell Programme

CAR T Cell Research Programme · Kelburn, Wellington
Department CAR T Cell Research Programme
Employment Type 1
Minimum Experience Experienced

An opportunity exists for an experienced and driven haematology or medical oncology registrar to work as a Clinical Fellow for the Malaghan Institute’s established chimeric antigen receptor (CAR) T-cell programme in Wellington, New Zealand. This will be a full-time role, available from July 2021, and will be for a fixed term of one or two years, depending on the applicant.

 

As our new Clinical fellow Fellow will be based at the Malaghan Institute, and will spend time at Wellington Blood & Cancer Centre and at the Clinical Trials Unit at Capital & Coast District Health Board. You will report to the Clinical Director Dr Robert Weinkove, and will work with the other Investigators, Clinical Trials Nurses, Quality Facilitator and CAR T-cell GMP team to gain experience in CAR T-cell delivery, toxicity management, clinical trial design and conduct, and cellular therapy quality systems. This Fellowship can be combined with a post-graduate degree qualification.

 

The Malaghan Institute of Medical Research (MIMR) is New Zealand’s leading independent biomedical research institute, with a focus on breakthrough discoveries in immunology and immunotherapy. We have over 100 staff committed to finding cures for diseases using the body’s own immune system. We are currently enrolling to a phase I clinical trial of a new third-generation chimeric antigen receptor (CAR) T-cell therapy for patients with relapsed and refractory non-Hodgkin lymphoma (ClinicalTrials.gov reference NCT04049513).

 

Our successful applicant will be proactive and enthusiastic, show effective time management skills, and be able to work with clinicians, allied health workers and scientists. An analytical thinker, you will be proficient in solving problems, from initial information gathering to a well-considered solution and subsequent monitoring and evaluation.

 

Applicants must hold or be eligible for registration with the New Zealand Medical Council. Applicants must have the legal right to work in New Zealand.


The Malaghan Institute is committed to Vision Mātauranga, and supports Māori health advancement in partnership with Te Urungi Māori, the Institute’s Māori advisory group. We welcome Māori applicants for this role. The Malaghan Institute is an equal opportunity employer, and values diversity. The Institute does not discriminate on the basis of race, religion, colour, national origin, gender, sexual orientation, age, marital status, or disability status.

 

Education and experience

  • Medical degree MBBS or equivalent is required
  • Completion of Royal Australasian College of Physicians (RACP) Basic Physician Training, including RACP Written and Clinical Examinations, or an equivalent qualification, is required
  • Completion of at least 2 years of Advanced Training in Clinical Haematology or Medical Oncology is required; trainees who in their final year of Advanced Training, or who have completed Advanced Training are particularly encouraged
  • Experience in at least one of lymphoma treatment, stem cell transplantation, and/or the conduct and reporting of clinical trials is required.

 

Key skills

  • Competency and specialist knowledge in the diagnosis and management of patients with lymphoma and related malignancies
  • Understanding of the basic principles of clinical research methodology
  • Willingness and enthusiasm to work within a multidisciplinary team of laboratory scientists, quality personnel and health care professionals 
  • Analytical skills to draft and edit complex documents related to cell therapy protocols and procedures
  • Competency in procedures such as lumbar puncture and bone marrow biopsy is desirable

 

Role Responsibilities

  • Undertake required training at the Malaghan Institute or at CCDHB
  • Conduct CAR-T cell trial procedures in conjunction with a trial nurse, from initial participant consent through to follow-up and management of adverse events.
  • Contribute to trial-related activities and committees
  • Develop cellular therapy quality procedures and documentation, in conjunction with clinical and GMP teams
  • Complete case report forms, adverse event reports and trial database data entry, in conjunction with trial coordinator and investigators.
  • Contribute to other clinical studies and publications in the field of lymphoma, leukaemia, myeloma or cellular therapies

 

Benefits

  • Exposure to a unique research environment working with highly driven scientists and support staff
  • A supportive team culture
  • Training and development opportunities to support you in your career with us, with potential for career progression, including support to undertake a higher degree (Masters or Diploma)
  • Opportunities for overseas travel and conference attendance
  • Employee Assistance Programme (EAP) – confidential, professional services which can support and guide you through your life or work challenges
  • An excellent location, with offices at Victoria University in Kelburn offering cafes and other amenities
  • Access to a range of services from Victoria University’s Research library
  • Salary of $84k-$120k depending on level of registrar experience.

 

If you share the Malaghan Institute’s passion for curing disease, and think you’d be a valuable addition to our CAR T-cell Programme, apply now by sending your cover letter and CV. Applications close 5pm Sunday 7 February 2021 for an anticipated July start. Interviews may be held throughout should the right candidate apply. Don’t wait, apply today!

 

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  • Location
    Kelburn, Wellington
  • Department
    CAR T Cell Research Programme
  • Employment Type
    1
  • Minimum Experience
    Experienced